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Brief practical guidelines for biologic prescriptions in severe asthma. Expert opinion| Rassegna di Patologia dell'Apparato Respiratorio
V. 39: Fascicolo 3 - Settembre 2024
Articolo di revisione
Pubblicato: 2024-12-19
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Brief practical guidelines for biologic prescriptions in severe asthma. Expert opinion

Pneumology Department, Azienda USL Toscana Sud-Est, “Misericordia” Hospital, Grosseto, Italy
Pneumology Unit, Azienda Socio Sanitaria Territoriale ASST Rhodense, Garbagnate Milanese (Milan), Italy
Pulmonology Unit, S. Valentino Hospital, Montebelluna (TV), AULSS2 Marca Trevigiana, Italy
Pulmonology Unit, Mater Salutis Hospital, Legnago (Verona), Italy
Pulmonary Unit, Integrated University Hospital of Verona, Verona, Italy
severe asthma biologic guidelines practical prescription

Abstract

This brief paper is intended to be a quick guide to prescribe biologics in severe asthma by following Global Initiative for Asthma (GINA) guidelines but also considering the author’s personal opinions. The paper starts with the identification of candidates for biologic therapy examining next the biological markers to be taken into account for the phenotyping of inflammation. Finally, it indicates the type of biologic to be chosen. This guide also points out the possible signals that can allow us to identify patients with severe asthma that would otherwise be ignored. Furthermore, it tries to give some directions on how to proceed in order to select the right biologic in the cases where the overlapping of different phenotypes can be found or in non-T2 asthma.

Affiliazioni

Bruno Sposato

Pneumology Department, Azienda USL Toscana Sud-Est, “Misericordia” Hospital, Grosseto, Italy

Francesco Bini

Pneumology Unit, Azienda Socio Sanitaria Territoriale ASST Rhodense, Garbagnate Milanese (Milan), Italy

Francesco Menzella

Pulmonology Unit, S. Valentino Hospital, Montebelluna (TV), AULSS2 Marca Trevigiana, Italy

Silvia Tognella

Pulmonology Unit, Mater Salutis Hospital, Legnago (Verona), Italy

Claudio Micheletto

Pulmonary Unit, Integrated University Hospital of Verona, Verona, Italy

Licenza

Creative Commons License

Questo lavoro è fornito con la licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 4.0 Internazionale.

Copyright

© Associazione Italiana Pneumologi Ospedalieri – Italian Thoracic Society (AIPO – ITS) , 2024

Come citare

Sposato, B., Bini, F., Menzella, F., Tognella, S., & Micheletto, C. (2024). Brief practical guidelines for biologic prescriptions in severe asthma. Expert opinion. Rassegna Di Patologia dell’Apparato Respiratorio, 39(3). Recuperato da https://www.aiporassegna.it/article/view/748
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